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. 2022 Nov 28;23(23):14876. doi: 10.3390/ijms232314876

Table 2.

Linear regression models for the morning BDNF and proBDNF protein levels in OSA patients.

Parameters Included in the Linear Regression BDNF Morning Protein Level ProBDNF Morning Protein Level
(r2 = 0.633, F = 14.639, p < 0.001) (r2 = 0.524, F = 9.355, p = 0.002)
B t p B t p
Age −0.389 −2.496 0.023 −0.395 −2.327 0.033
Total Sleep Time (TST) 0.073 0.342 0.737 0.031 0.149 0.883
HIF-1α morning protein level −0.246 −1.678 0.113 −0.542 −3.192 0.005
Basal SpO2 −0.164 −0.741 0.470 −0.237 −1.363 0.192
Mean SpO2 of desaturations during sleep −0.577 −3.707 0.002 −0.183 −0.999 0.333

Abbreviations: BDNF—brain-derived neurotrophic factor, HIF-1—hypoxia-inducible factor 1, OSA—obstructive sleep apnea, SpO2—oxygen saturation.