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. 2022 Nov 28;23(23):14871. doi: 10.3390/ijms232314871

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of HBU651 on the lipid and biochemical profiles in the blood of HFD-induced obese mice. (A) Total-cholesterol (Total-C), (B) LDL-cholesterol (LDL-C), (C) HDL-cholesterol (HDL-C), (D) Free fatty acid (FFA), (E) Phospholipids (PL), (F) Triglyceride (TG), (G,H) Liver function marker enzyme activities of AST (G) and ALT (H), (I) Creatinine, (J,K) ELISA. Serum protein levels of TNF-α (J) and MCP-1 (K). Data are expressed as means ± SEM (n = 5). ^# p < 0.05, ^### p < 0.001 vs. NC, and * p < 0.05, ** p < 0.01 vs. HFD-control. NC, normal chow; Control, HFD-control; HBU10, HFD plus HBU651 10 mg/kg; HBU30, HFD plus HBU651 30 mg/kg.