Table 4.

Partial distribution of lung cancer health factors sorted by category and connection delta ratio (cutoff=0.5) as examples. The full distribution of lung cancer health factors is provided in Table A1 in Multimedia Appendix 1.

Categorya	Local code	Term	Value	Connection delta ratio	Tag
dac	C-182460	Left lung pulmonary obstructive pneumonia	TRUE	1.00	confirmed
dac	C-248056	Right lung pulmonary obstructive pneumonia	TRUE	1.00	confirmed
dac	C-765209	Obstructive pneumonia	TRUE	1.00	confirmed
dac	C-305976	Pneumothorax	TRUE	0.93	correlated
dac	C-172569	Bacterial Infection	TRUE	0.88	correlated
lab	C-659218	Hepatitis B virus	TRUE	1.00	correlated
lab	C-493765	Squamous cell carcinoma antigen	up	0.90	confirmed
lab	C-573086	Neuron-specific enolase measurement	up	0.82	correlated
lab	C-952408	Non-small cell lung cancer associated-antigen	up	0.82	confirmed
lab	C-103698	Superoxide dismutase measurement	down	0.82	correlated
obs	C-039824	Mediastinal mass	TRUE	1.00	confirmed
obs	C-706432	Lung mass	TRUE	1.00	confirmed
obs	C-748932	Lung mass found in checkup	TRUE	1.00	confirmed
obs	C-134276	Lung shadow	TRUE	0.91	confirmed
obs	C-706281	Bronchial stenosis	TRUE	0.89	correlated
rf	C-902187	Smoking	TRUE	0.50	confirmed
smp	C-549780	Pain	TRUE	1.00	confirmed
smp	C-289547	Bloodstained sputum	TRUE	0.96	confirmed
smp	C-152064	Hemoptysis (cough up blood)	TRUE	0.83	correlated
smp	C-243071	Shoulder Pain	TRUE	0.82	confirmed
smp	C-127089	Hoarseness	TRUE	0.80	correlated

^aCategories include condition (dac), laboratory test (lab), observation (obs), risk factor (rf), and symptom (smp).