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. 2022 Nov 22;23(23):14516. doi: 10.3390/ijms232314516

Figure 5.

Figure 5

Upregulation of YAP1 and TAZ in rodent models of pulmonary hypertension. (A) Representative Western blot images and Lamin B-normalized quantification of protein demonstrate that YAP1 expression has an increasing trend in mouse lungs after 4 weeks of hypoxia exposure; (B) representative Western blot images and Lamin B-normalized quantification of protein demonstrate that YAP1 expression increased significantly in lung tissues from monocrotaline (MCT)-mediated pulmonary hypertension in rats; (C) representative Western blot images and Lamin B-normalized quantification of protein demonstrate that YAP1 expression increased significantly in lung tissues from hypoxia + Sugen-mediated pulmonary hypertension in rats; (D) representative Western blot images and Lamin B-normalized quantification of protein demonstrate that TAZ expression increased significantly in lung tissues from hypoxia + Sugen-mediated pulmonary hypertension in rats. ** p < 0.01 versus controls, n = 3–4 per group.