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. 2022 Dec 2;23(23):15155. doi: 10.3390/ijms232315155

Figure 3.

Figure 3

Baicalin is a potent TRPV4 inhibitor. (A,B) Representative images of immunoblot analysis of mTOR, p-Akt, and Akt in A375 cells treated with HC067047 for 24 h. (C,D) Representative images of immunoblot analysis of mTOR, p-Akt, and Akt in A375 cells treated with Baicalin for 24 h. (E,F) CETSA using intact cells, which were exposed to 200 μM Baicalin. (G,H) Baicalin promotes TRPV4 protein resistance to proteases (DARTS). Data are expressed as means ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001.