Figure 6.

The effect of pharmacological inhibition of lipid handling proteins on the cell cycle distribution of OC cells. A2780 cells were incubated in control medium (0 µM, white bars) or in medium containing various concentrations (gray bars) of small molecule inhibitors of cellular lipid handling proteins at 37 °C for 48 h. Thereafter, cell cycle distribution was analyzed by flow cytometry. Results show relative cell numbers in percent of total and represent the means ± SD of three independent experiments. The level of significance was determined by ANOVA followed by Scheffe test, p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***) compared to control (0 µM, white bars).