Figure 3.

After trauma, expression of the CXCR-4 increases, and residual fat-derived stem cells from the area of the hair follicles, sweat glands, and nerve endings are recruited to regulate the local inflammatory response. Overexpression of the SDF-1 protein is responsible for cell migration in the early stages of wound healing. ADSCs promote the shift of the macrophage population from M1 to M2 and stimulate the secretion of anti-inflammatory TNF and IL-10. Images purchased under the Adobe Stock License.