FIG. 8.

The difference in E. coli ingestion between 129/ICR and SR-A^−/− BMMφ is strain dependent. BMMφ from SR-A^−/− or 129/ICR mice were incubated with paraformaldehyde-fixed RdGnX-labelled E. coli DH5α or K1 (60 bacteria per Mφ) in the presence or absence of poly(I). —, fluorescence obtained by flow cytometry for the Mφ populations incubated with E. coli alone; ––––, fluorescence for the Mφ populations incubated with E. coli in the presence of poly(I). Poly(I)-treated 129/ICR Mφ displayed 30% less mean fluorescence (significant at P = 0.01).