Table 1.
Sample characteristics of 338 combined WRAP and Wisconsin ADRC IMPACT participants.
| Characteristics | WRAP (n=133) | IMPACT (n=205) | Total (N=338) | |||
|---|---|---|---|---|---|---|
| n | % | n | % | n | % | |
| Gender | ||||||
| Male | 51 | 38.3 | 61 | 29.8 | 112 | 33.1 |
| Female | 82 | 61.7 | 144 | 70.2 | 226 | 66.9 |
| Caffeine intake* | NA |
NA |
||||
| Less than once per day | 33 | 25.0 | ||||
| 1–2 per day | 59 | 44.7 | ||||
| 3–5 per day | 35 | 26.5 | ||||
| 6 or more per day | 5 | 3.8 | ||||
| Mean | SD | Mean | SD | Mean | SD | |
| Age of CSF collection + | 65.4 | 6.7 | 58.9 | 5.7 | 61.5 | 6.9 |
| MMSE at CSF collection + | 29.5 | 0.9 | 29.4 | 0.8 | 29.4 | 0.8 |
| Age at MRI + | 66.9 | 6.6 | 61.7 | 6.1 | 63.5 | 6.8 |
| Age at PiB DVR + | 67.1 | 6.7 | 63.7 | 4.8 | 66.4 | 6.5 |
| Years of education | 16.5 | 2.6 | 16.2 | 2.3 | 16.3 | 2.4 |
| p-tau + | 18.9 | 7.5 | 15.8 | 5.8 | 17.0 | 6.7 |
| t-tau + | 212.9 | 75.1 | 182.9 | 67.3 | 194.7 | 71.9 |
| Aβ42 + | 868.6 | 390.0 | 917.6 | 363.5 | 898.3 | 374.3 |
| Aβ42/40 + | 0.06 | 0.02 | 0.07 | 0.01 | 0.06 | 0.02 |
*
Within WRAP, one participant did not report caffeine intake, n=132. The summary statistics of caffeine intake was based on the baseline visit.
NA: the caffeine intake data were not available in the IMPACT cohort.
+
For the AD biomarkers, the last available visit was used.