Table 2.

Results from linear regression models for four core AD CSF biomarkers.

	p-tau>			t-tau			Aß42			Aß42/40
PC	Estimate	p	adjusted p	Estimate	p	adjusted p	Estimate	p	adjusted p	Estimate	p	adjusted p
1	−0.5238	1.53E-01	1.00E+00	−0.4901	1.91E-01	1.00E+00	0.1963	4.71E-01	1.00E+00	0.5357	2.04E-01	1.00E+00
2	−0.6802	9.61E-02	1.00E+00	−0.4695	2.60E-01	1.00E+00	0.2779	3.59E-01	1.00E+00	0.6674	1.55E-01	1.00E+00
3	0.5286	1.13E-01	1.00E+00	0.5640	9.78E-02	1.00E+00	0.2209	3.72E-01	1.00E+00	−0.1761	6.44E-01	1.00E+00
4	−0.7265	1.79E-02	5.38E-01	−0.6778	3.25E-02	9.75E-01	−0.5178	2.43E-02	7.30E-01	−0.1791	6.11E-01	1.00E+00
5	0.8594	4.02E-03	1.21E-01	0.8667	4.47E-03	1.34E-01	0.5028	2.34E-02	7.01E-01	−0.0255	9.41E-01	1.00E+00
6	−0.4597	1.15E-01	1.00E+00	−0.4448	1.37E-01	1.00E+00	−0.4066	6.08E-02	1.00E+00	−0.1109	7.41E-01	1.00E+00
7	0.0622	8.21E-01	1.00E+00	0.1649	5.57E-01	1.00E+00	0.3540	8.20E-02	1.00E+00	0.4180	1.86E-01	1.00E+00
8	−0.7601	2.92E-03	8.77E-02	−0.7680	3.19E-03	9.57E-02	−0.6323	8.03E-04	2.41E-02	−0.2317	4.32E-01	1.00E+00
9	−0.2758	2.45E-01	1.00E+00	−0.2240	3.54E-01	1.00E+00	0.1087	5.36E-01	1.00E+00	0.1861	4.92E-01	1.00E+00
10	0.3075	1.76E-01	1.00E+00	0.4192	7.07E-02	1.00E+00	0.0008	9.96E-01	1.00E+00	−0.1394	5.91E-01	1.00E+00
11	−0.2276	2.95E-01	1.00E+00	−0.2408	2.77E-01	1.00E+00	0.1113	4.89E-01	1.00E+00	0.5172	3.77E-02	1.00E+00
12	0.4771	1.44E-02	4.32E-01	0.5012	1.23E-02	3.70E-01	0.4438	2.21E-03	6.63E-02	0.2316	3.02E-01	1.00E+00
13	−0.6286	7.42E-04	2.22E-02	−0.6503	6.15E-04	1.85E-02	−0.3306	1.69E-02	5.08E-01	0.0404	8.51E-01	1.00E+00
14	0.1981	2.46E-01	1.00E+00	0.1655	3.55E-01	1.00E+00	0.2351	7.00E-02	1.00E+00	0.1484	4.50E-01	1.00E+00
15	−0.0790	6.45E-01	1.00E+00	−0.1106	5.28E-01	1.00E+00	−0.1188	3.49E-01	1.00E+00	−0.2497	2.03E-01	1.00E+00
16	−0.6785	2.48E-05	7.43E-04	−0.7216	1.06E-05	3.18E-04	−0.3970	9.07E-04	2.72E-02	0.0535	7.74E-01	1.00E+00
17	−0.0901	5.64E-01	1.00E+00	−0.0787	6.21E-01	1.00E+00	−0.0113	9.22E-01	1.00E+00	0.1135	5.25E-01	1.00E+00
18	−0.2563	9.06E-02	1.00E+00	−0.2856	6.43E-02	1.00E+00	−0.2501	2.54E-02	7.62E-01	−0.1071	5.39E-01	1.00E+00
19	−0.1066	4.46E-01	1.00E+00	−0.1279	3.70E-01	1.00E+00	−0.0807	4.36E-01	1.00E+00	−0.0932	5.62E-01	1.00E+00
20	−0.4409	5.04E-04	1.51E-02	−0.4517	4.72E-04	1.42E-02	−0.0971	3.05E-01	1.00E+00	0.2028	1.67E-01	1.00E+00
21	−0.1416	2.70E-01	1.00E+00	−0.1000	4.50E-01	1.00E+00	0.0278	7.72E-01	1.00E+00	0.0714	6.27E-01	1.00E+00
22	−1.0058	1.61E-16	4.84E-15	−1.0686	7.23E-18	2.17E-16	−0.5130	3.47E-08	1.04E-06	0.0160	9.13E-01	1.00E+00
23	0.3025	1.38E-02	4.14E-01	0.2765	2.81E-02	8.43E-01	0.0230	8.02E-01	1.00E+00	−0.2818	4.57E-02	1.00E+00
24	−0.0896	4.54E-01	1.00E+00	−0.1217	3.19E-01	1.00E+00	−0.1339	1.31E-01	1.00E+00	−0.1206	3.79E-01	1.00E+00
25	0.1733	1.30E-01	1.00E+00	0.1587	1.74E-01	1.00E+00	0.1556	6.62E-02	1.00E+00	0.0774	5.57E-01	1.00E+00
26	−0.0200	8.54E-01	1.00E+00	−0.0514	6.42E-01	1.00E+00	−0.0424	5.98E-01	1.00E+00	−0.0856	4.91E-01	1.00E+00
27	0.1214	2.63E-01	1.00E+00	0.0959	3.87E-01	1.00E+00	−0.0214	7.90E-01	1.00E+00	−0.1003	4.18E-01	1.00E+00
28	0.0674	5.24E-01	1.00E+00	0.0792	4.63E-01	1.00E+00	0.0166	8.32E-01	1.00E+00	−0.0932	4.42E-01	1.00E+00
29	−0.3401	7.13E-04	2.14E-02	−0.3382	9.87E-04	2.96E-02	−0.0536	4.75E-01	1.00E+00	0.1359	2.42E-01	1.00E+00
30	0.1393	1.69E-01	1.00E+00	0.1815	7.84E-02	1.00E+00	0.1705	2.24E-02	6.73E-01	0.1706	1.42E-01	1.00E+00

The adjusted p values were calculated based on the Bonferroni adjustment for 30 PCs.