Table 1.

Circular RNAs and their role in the different ovaries.

Species	Tissue	CircRNA	Target miRNA/Gene/Protein	Function	Ref.
human	OC	Cdr1as	miR-1270/SCAI	sensitizes ovarian cancer to cisplatin	[54]
		circ-ITCH	miR-145/RASA1	inhibit tumour progression	[75]
		has_circ_0051240	miR-637/KLK4	suppresses cell proliferation, migration, and invasion	[76]
		circEPSTI1	miR-942	inhibit cell growth and invasion, induces apoptosis	[77]
		circRNA CDR1	miR-135b-5p/HIF1AN	decreasing the occurrence and progression of ovarian cancer	[78]
		circLARP4		down-regulated in cancerous ovarian cells	[79]
		hsa_circ_0007444	miR-23a-3p/DICER1		[80]
		circPLEKHM3	miR-320a/SMG1	exacerbated the effect of curcumin on ovarian cancer cell proliferation and apoptosis, as well as the anti-tumour effect	[81]
		circABCB10	miR-1271	promotes cell proliferation and invasion but inhibits apoptosis	[82]
		circRNA1656	miR-1301-3p/miR-4660-SIRT3	down-regulated in HGSOC	[53]
		circ-CSPP1	miR-1236-3p	promotes proliferation, invasion, and migration	[83]
		has-circ-001567		promotes cell proliferation and invasion	[84]
		circ-SMAD7	KLF6	promotes cell proliferation and invasion	[85]
		circ_0025033	miR-184/LSM4	promotes the progression of ovarian cancer	[86]
		circHIPK3		related to cell growth, migration, and apoptosis	[52]
	PCOS	circ_0023942	CDK-4	inhibit granulosa cell proliferation	[87]
		circ_0043533	miR-1179	related to Bcl-2, CDK2, and Cyclin D1	[88]
		circ_RANBP9	miRNA-136-5p/XIAP	exacerbates POS	[89]
		circASPH	miR-375/MAP2K6	promotes cells proliferation	[90]
		circRHBG	miR-515/SLC7A11	knockdown of circRHBG promotes ferroptosis in PCOS	[91]
		circ_0005925	miR-324-3p/MAP2K6	Promotes Granulosa Cell Growth	[92]
		circ_0043532	miR-182/SGK3	promote cell proliferation	[93]
	ovary	circDDX10		ovarian aging	[58]
	KGN	circUSP36	PTBP1/NEDD4L	enhance autophagic granulosa cell death	[94]
	GCs	circDDX10		affecting the proliferation and apoptosis and steroid hormone synthesis	[95]
Pig	ovary	circ-TCP11	miR-183	associated with swine litter size	[70]
	ovary	circSCIN	miR-133, miR-148a/b	affecting estrogen secretion	[71]
	GCs	ssc-circINHA-001	miR-214-5p, miR-7144-3p, miR-9830-5p/INHBA	mediated Inhibin–Activin balance	[66]
	GCs	circSLC41A1	miR-9820-5p/SRSF1	resists porcine granulosa cell apoptosis and follicular atresia	[67]
	GCs	circ-ANKHD1	miR-27a-3p/SFRP1	decreased the cell apoptosis rates	[96]
Bovine	GCs	circ_n/a_75	miR-339a	growth factor response	[64]
		circ_n/a_303	miR-2400 and miR-30c		[64]
Goat	follicles	chi_circ_0008219	miR-34c-5p, miR-483, miR-1468-3p	higher fecundity rate	[72]
Mouse	GCs	circEGFR	miR-125a-3p/CYP19A1	promoted granulosa cell apoptosis	[59]