Table 2.

Natural TRPV3 inhibitors.

Natual Compound (Ref.)	Source	Treated
Isochlorogenic acid isomers [39]	Forsythia suspensa	AD
Tribulus terrestris [63]	fruit extract, small leafy plant	AD, the regulation of calcium channels and TRPV3
Spirodelae Herba (SH) [64]	Spirodela polyrhiza	AD, modulation of TRPV3, skin barrier pathologies in AD
Forsythoside B [65]	Lamiophlomis rotate or Forsythia suspensa	Pruritus, selective inhibition of TRPV3 channels
Verbascoside [66]	Lamiales	Pruritus and anti-inflammatory effects
Scutellarein [67]	Scutellaria lateriflora, genus Scutellaria, fern Asplenium belangeri	Dermatitis, skin inflammation
17R-RvD1 [68,69]	mammalian tissues	Acute pain behaviours
Citrusinine-II [70]	Atalantia monophylla	Pruritus, pain and other skin complaints