Figure 5.

(A) GPx activity in thyroid tissues; (B) correlation between GPx activity and H₂O₂ generation in benign nodules and malignant thyroid tumors; (C) correlation between GPx activity and H₂O₂ generation in normal contralateral tissues. N = normal contralateral tissue; PTC = papillary thyroid cancer; PTC ALL = all papillary thyroid carcinoma cases; PTC ALL MUT = PTCs with any mutation; PTC non MUT = PTCs without mutations detected (see Methods section); NIFTP = non-invasive follicular thyroid neoplasms with papillary-like nuclear features; FA = follicular adenoma; HA = Hurtle cell adenoma; FTC = follicular thyroid carcinoma; PDTC/ATC = poorly differentiated thyroid cancer/anaplastic thyroid cancer.