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. 2022 Dec 10;72:102907. doi: 10.1016/j.ctim.2022.102907

Table 1.

Baseline characteristics of trials included in meta-analysis.

Study
(Ref. #)
Year Quality Score Randomization Types of ozone therapy n Age, years (SD) Male, % BMI, kg/m2 (SD)
Araimo19 2021 17 Randomized Autohemotherapy
Blank
14
14
63.3 (12.1)
60.1 (14.4)
64
50
28.2 (4.6)
28.9 (3.2)
Çolak5 2021 14 Non-randomized Autohemotherapy
Blank
37
18
58.0 (16.3)
64.7 (10.4)
51.4
55.6
NR
NR
Dengiz20 2022 16 Randomized Nebulization
Blank
15
15
51.6 (16.9) ^ 60
53
NR
NR
Fernández-Cuadros21 2021 14 Non-randomized Intra-rectal
Blank
14
14
84.4 (9.5)
83.0 (12.6)
86
50
NR
NR
Hernández22 2021 12 Non-randomized Autohemotherapy
Blank
9
9
64 (11)
71 (18)
78
67
26.2 (4.5)
29.5 (7.1)
Shah23 2021 15 Randomized Intra-rectal + Autohemotherapy
Blank
30
30
44.0 (8.7)
43.6 (9.7)
87
73
NR
NR
Sozio24 2021 17 Randomized Autohemotherapy
Blank
48
44
63.5 (12.5)
64.2 (14.1)
64.6
54.5
26.6 (4.5)
27.4 (6.0)
Tascini25 2021 12 Non-randomized Autohemotherapy
Blank
30
30
57 (12)
65 (13)
77
60
NR
NR

Abbreviations: BMI, body mass index; NR, not reported; SD, standard deviation. ^ Average value of both groups.