Table 1.

Effect of different solvents on synthesizing the fused cholestane pyrrole 3a at reflux.

Entry	Solvent [a]	Reaction Time (h) [b]	Yield of 3a (%) [c]
1	acetonitrile	6	38
2	ethanol	6	45
3	toluene	5	80
4	xylene	5	65
5	DMF	6	32

^[a] All the reactions were conducted at reflux, except for DMF where the temperature was kept controlled at 150 °C, as at higher temperatures, multiple degradation products were observed. ^[b] Maximum yield occurred within these reaction times. ^[c] Isolated yields.