Table 3.
Factors associated with response to induction therapy. Multivariate regression logistic for response to induction treatment. Effect of patient and disease characteristics on best response to treatment (complete remissions) and multivariate analyses (prognostic factors with p < 0.1 in univariate analysis were included).
| Variable | OR | Significance | Lower CI | Upper CI |
|---|---|---|---|---|
| Age | 0.980 | p < 0.001 | 0.973 | 0.987 |
| WBC (×1000/mL) | 0.996 | p < 0.001 | 0.994 | 0.998 |
| Cytogenetic risk | ||||
| Low risk vs. intermediate risk | 0.341 | p < 0.001 | 0.222 | 0.523 |
| Low risk vs. High risk | 0.145 | p < 0.001 | 0.093 | 0.226 |
| NPM1 mutation | ||||
| Absence vs. presence | 2.865 | p < 0.001 | 2.235 | 3.674 |
| Ratio FLT3–ITD > 0.5 | ||||
| Absence vs. presence | 0.617 | p = 0.005 | 0.441 | 0.862 |