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. 2022 Dec 9;21:278. doi: 10.1186/s12933-022-01711-5

Table 5.

The effect of 1 standard deviation increase in risk scores or clinical biomarkers on echocardiographic parameters

Variable Standardized β, p-value R2
ARIC-HF^ WATCH-DM^ NTpBNP* hs-TnT* ARIC-HF^ WATCH-DM^ NTpBNP* hs-TnT*
GLS 0.22, p < 0.001 0.22, p < 0.001 0.32, p < 0.001 0.26, p < 0.001 0.05 0.05 0.18 0.14
E/e’ 0.09, p = 0.015 0.33, p < 0.001 0.32, p < 0.001 0.29, p < 0.001 0.01 0.11 0.17 0.16
e’ −0.07, p = 0.060 −0.27, p < 0.001 −0.12, p = 0.001 −0.15, p = 0.001 0.005 0.08 0.08 0.09
LAVi 0.01, p = 0.813 0.23, p < 0.001 0.22, p < 0.001 0.15, p = 0.001 0.0001 0.04 0.10 0.06
LVMi 0.09, p = 0.014 0.23, p < 0.001 0.15, p < 0.001 0.24, p < 0.001 0.008 0.05 0.07 0.09

^univariable linear regression analysis, *multivariable linear regression analysis adjusted for age, body mass index and renal function

95% CI = 95% confidence interval; GLS = global longitudinal strain; hs-TnT = high sensitivity troponin-T; LAVi = left atrial volume indexed to body surface area; LVMi = left ventricular mass indexed to body surface area