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The mechanism of chemoresistance in cancer cells may include a variety of molecular mechanisms, such as regulating drug influx and efflux through ABC transporters, inhibiting cell death, altering drug targets, regulating epigenetic factors, inactivating chemotherapeutic agents, inactivating tumor suppressor genes, modifying DNA repair processes, and modulating growth factor signaling (adapted from [33], License Number: 5433490420433, License date: 21 November 2022).
