Table 2.
Effect of SintMed150 on behavioral and general appearance of male BALB/c mice.
| Behavior and General Appearance | Observations | ||
|---|---|---|---|
| Vehicle | SintMed150 (50 mg/kg) |
SintMed150 (100 mg/kg) |
|
| Changes in the eyes | No changes | No changes | No changes |
| Changes in the fur | No changes | No changes | No changes |
| Changes in the skin | No changes | No changes | No changes |
| Coma | Absent | Absent | Absent |
| Convulsions | Absent | Absent | Absent |
| Diarrhea | Absent | Absent | Absent |
| Lethargy | Absent | Absent | Absent |
| Salivation | Absent | Absent | Absent |
| Sleep | Usual | Usual | Usual |
| Tremors | Absent | Absent | Absent |
The animals were observed daily for 14 days.