Skip to main content
. 2022 Dec 6;11(23):3939. doi: 10.3390/cells11233939

Figure 4.

Figure 4

Phytocannabinoids improve wound healing in healthy and SIPS CCD-1064Sk (PDL 24) human dermal fibroblasts. (A) Percentage of the unhealed wounds at 24, 48, and 72 h after the scratch assay was performed with healthy dermal fibroblasts exposed to 2 µM of THC or CBD. (B) Percentage of the unhealed wounds at 24, 48, and 72 h after the scratch assay was performed with SIPS dermal fibroblasts exposed to 2 µM of THC or CBD. Data were analyzed with an ANOVA test followed by a Dunnett’s post-hoc multiple comparison test compared to the vehicle. Bars represent mean ± SEM, n = 6. Significance is indicated using the following scale: * p < 0.05, ** p < 0.01, *** p < 0.001. CBD, cannabidiol; DMSO, dimethyl sulfoxide (vehicle); SIPS, stress-induced premature senescence; THC, delta-9-tetrahydrocannabinol.