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. 2022 Dec 3;14(23):5134. doi: 10.3390/nu14235134

Figure 1.

Figure 1

Respiratory quotient (RQ) (A), carbohydrate (CH) oxidation (B) fat oxidation (C) and energy expenditure (EE) (D), locomotor activity (E) and number of rearings (F) measured by indirect calorimetry analyses at day 19 of lactation of dams treated with either CCX (CCX group) or vehicle (VEH group) during lactation. Expression levels of adiponectin metabolism-related genes in mammary gland (I) and OWAT (J) as well as the concentration of total lipids (H) and lipid-related metabolites (G) in the mammary gland are also shown. Data are the mean ± SEM (n = 8–9). * Effect of CCX treatment (Student’s t test, p < 0.05). CCX, cocoanox extract; TG, triglycerides; DHA, docosahexaenoic acid; Adipor1, adiponectin receptor 1; Adipor2, adiponectin receptor 2; Adipoq, adiponectin; Ero1-Lα, endoplasmic reticulum oxidoreductin 1-like protein alpha; DsbAL, disulfide-bond-A oxidoreductase-like protein; Cd36, fatty acid translocase, homologue of CD36; Fas, fatty acid synthase; Acc1, acetyl CoA carboxylase 1; Gpat, glycerol-3-phosphate acyltransferase; Dgat1, diacylglycerol O-acyltransferase 1; OWAT, ovarian white adipose tissue; Pparα, peroxisome proliferator-activated receptor alpha; Had, hydroxyacyl-CoA dehydrogenase; Atgl, adipose triglyceride lipase; Hsl, hormone-sensitive lipase.