Table 1.
Biometric, plasma parameters and energy intake of dams fed with chow and treated with vehicle or CCX during lactation.
| VEH | CCX | Student’s t-Test (p) | |
|---|---|---|---|
| Biometric parameters | |||
| Initial body weight (g) | 278 ± 3 | 278 ± 6 | 0.926 |
| Final body weight (g) | 286 ± 3 | 283 ± 5 | 0.561 |
| Body weight gain (g) | 8.00 ± 3.78 | 5.11 ± 5.28 | 0.662 |
| RWAT (g) | 3.15 ± 0.41 | 3.18 ± 0.39 | 0.954 |
| MWAT (g) | 1.87 ± 0.14 | 1.67 ± 0.17 | 0.388 |
| OWAT (g) | 4.93 ± 0.64 | 4.77 ± 0.39 | 0.830 |
| Adiposity index (%) | 3.81 ± 0.45 | 3.83 ± 0.39 | 0.977 |
| Mammary gland (g) | 11.0 ± 0.3 | 11.7 ± 0.3 | 0.096 |
| Liver (g) | 10.4 ± 0.1 | 10.0 ± 0.2 | 0.129 |
| Lean mass (g) | 249 ± 4 | 243 ± 6 | 0.452 |
| Lean mass (%) | 86.3 ± 0.7 | 85.9 ± 0.7 | 0.725 |
| Fat mass (g) | 23.1 ± 1.6 | 23.0 ± 2.9 | 0.987 |
| Fat mass (%) | 8.01 ± 0.59 | 8.20 ± 1.07 | 0.885 |
| Plasma parameters | |||
| Glucose (mmol/L) | 5.93 ± 0.15 | 5.57 ± 0.24 | 0.228 |
| Insulin (mU/L) | 43.9 ± 6.6 | 57.9 ± 19.7 | 0.516 |
| FFAs (mmol/L) | 0.218 ± 0.025 | 0.348 ± 0.043 * | 0.020 |
| HOMA-IR | 11.7 ± 2.0 | 15.5 ± 5.5 | 0.530 |
| R-QUICKI | 0.338 ± 0.007 | 0.339 ± 0.022 | 0.973 |
| Total adiponectin (µg/mL) | 17.6 ± 0.7 | 23.9 ± 1.9 * | 0.010 |
| HMW adiponectin (μg/mL) | 2.99 ± 0.55 | 3.93 ± 1.03 | 0.401 |
| Total adiponectin/g WAT | 1.72 ± 0.17 | 2.31 ± 0.20 * | 0.041 |
| Triglycerides (mmol/L) | 0.375 ± 0.024 | 0.353 ± 0.029 | 0.547 |
| Phospholipids (mmol/L) | 2.11 ± 0.07 | 2.03 ± 0.08 | 0.489 |
| Total cholesterol (mmol/L) | 2.21 ± 0.11 | 1.96 ± 0.07 | 0.065 |
| Energy intake (kcal/day) | 155 ± 2 | 147 ± 5 | 0.148 |
Dams were orally supplemented with CCX (200 mg.kg−1.day−1) (CCX group) or vehicle (VEH group) during lactation (21 days). Data are the mean ± SEM (n = 9). * p < 0.05 vs. VEH group (Student’s t-test). CCX, cocoanox extract; RWAT, retroperitoneal white adipose tissue; MWAT, mesenteric white adipose tissue; OWAT, ovarian white adipose tissue; FFAs, non-esterified free fatty acids; HOMA-IR, Homeostatic model assessment of insulin resistance; R-QUICKI, revised quantitative insulin sensitivity check index; HMW, high molecular weight; WAT, white adipose tissue. Total adiponectin/g WAT was computed as the quotient between the circulating levels of total adiponectin and the sum of the OWAT, MWAT and RWAT depot weights.