Table 1.
Baseline characteristics of study participants.
| Characteristic |
l-Arginine + Vitamin C (n = 23) |
Placebo (n = 23) |
Total (n = 46) |
|---|---|---|---|
| Age, years | 50.0 (16.5) | 51.0 (11.0) | 50.5 (14.0) |
| Women, n (%) | 15 (65.2) | 15 (65.2) | 30 (65.2) |
| BMI, kg/m2 | 24.8 (5.9) | 25.5 (6.5) | 25.0 (6.5) |
| Severity of acute COVID-19, n (%) | |||
| No hospitalization | 8 (34.8) | 12 (52.2) | 20 (43.5) |
| Hospitalization | 13 (56.5) | 9 (39.1) | 22 (47.8) |
| ICU admission | 2 (8.7) | 2 (8.7) | 4 (8.7) |
| Time from COVID-19 diagnosis, days | 240.0 (118.5) | 269.0 (127.0) | 254.0 (136.5) |
| 6 min walk test distance, m | 520.0 (49.5) | 540.0 (120.0) | 520.0 (90.0) |
| Handgrip, kg | 22.5 (16.0) | 22.6 (12.3) | 22.6 (14.4) |
| Flow-mediated dilation, % | 10.5 (5.2) | 8.9 (5.8) | 9.8 (6.0) |
| Serum l-arginine, µM | 167.2 (76.8) | 175.0 (93.1) | 170.6 (88.0) |
Abbreviations: BMI, body mass index; ICU, intensive care unit. Data are expressed as median (interquartile range) for continuous variables and number (percent) for categorical variables.