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. 2022 Dec 1;11(23):7152. doi: 10.3390/jcm11237152

Table 3.

IVS hypertrophy for the prediction of CHD, MI and stroke during follow up.

Subgroups CHD MI
Cases/Noncases Incidence HR (95% CI) p Value Case/Noncases Incidence HR (95% CI) p Value
Before Adjustment
Overall
Normal IVSd 120/4299 Reference / 51/4368 Reference /
IVS hypertrophy 26/356 2.757 (1.802–4.219) <0.001 16/366 4.157 (2.357–7.332) <0.001
Male
Normal IVSd 46/2130 Reference / 22/2154 Reference /
IVS hypertrophy 9/148 2.893 (1.414–5.917) 0.004 4/153 2.732 (0.938–7.96) 0.065
Female
Normal IVSd 74/2169 Reference / 29/2214 Reference /
IVS hypertrophy 17/208 2.558 (1.507–4.344) <0.001 12/213 4.951(2.497–9.817) <0.001
After Adjustment
Overall
Normal IVSd 120/4299 Reference / 51/4368 Reference /
IVS hypertrophy 26/356 1.818 (1.155–2.816) 0.01 16/366 2.410 (1.303–4.458) 0.005
Male
Normal IVSd 46/2130 Reference / 22/2154 Reference /
IVS hypertrophy 9/148 1.873 (0.875–4.008) 0.106 4/153 1.639 (0.516–5.208) 0.402
Female
Normal IVSd 74/2169 Reference / 29/2214 Reference /
IVS hypertrophy 17/208 1.870 (1.062–3.292) 0.030 12/213 3.063 (1.449–6.474) 0.003

Adjusted for Sex, Age, DM, BMI, Current_smoke, Current_drink, FamilyHis, Mean_SBP, Mean_DBP, GLU, LDL_C, HDL_C as appropriate. Abbreviations: CHD, coronary heart disease; MI, myocardial infarction; IVSd, interventricular septum thickness; IVS hypertrophy, interventricular septum hypertrophy.