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. 2022 Nov 22;23(23):14518. doi: 10.3390/ijms232314518

Figure 8.

Figure 8

N-acetylcysteine inhibits concentration and time-dependent on the effects of SARS-CoV-2 mosaic (S-E-M) on inflammatory cytokines. (A) Differentiated U937 macrophages and (B) bronchial epithelial BEAS2B were incubated with N-acetylcystine (NAC) at 16 µM, 35 µM, 1.6 mM, and 5 mM for 24 h, 72 h, and 144 h, followed by the stimulation with mosaic (S-E-M) 50 ng/mL for 24 h. Cell supernatants were collected to measure different cytokines by ELISA. Data are presented as scatter dot blot of n = 4 independent experiments run in triplicate, with median and interquartile range values. Statistical analysis was carried out using by Kruskal-Wallis test and Dunn’s post hoc test for multiple comparisons. * p < 0.05 vs. control. # p < 0.05 vs. mosaic (S-E-M) stimulus.