4-HNE | 4-hydroxy-2-nonenal |
β3-AR | beta-3 adrenergic receptor |
8-OHdG | 8-hydroxydeoxyguanosine |
ACC | acetyl-CoA carboxylase |
Aldh1a1 | aldehyde dehydrogenase family 1 member A1 |
AGIQ | alpha-glycosyl isoquercitrin |
ALP | alkaline phosphatase |
AMP | adenosine monophosphate |
AMPK | 5′AMP-activated protein kinase |
apoE | apolipoprotein E |
AUC | area under the plasma concentration–time curve |
BHT | butylated hydroxytoluene |
BrdU | 5-bromo-20-deoxyuridine |
BUN | blood urea nitrogen |
CAR | constitutive androstane receptor |
CD3 | cluster of differentiation 3 |
Chrm2 | cholinergic receptor, muscarinic 2 |
Chrna7 | cholinergic receptor nicotinic alpha 7 subunit |
Cmax | maximum plasma concentration |
Cox2 | cyclooxygenase-2; prostaglandin-endoperoxide synthase 2 |
COXIV | cytochrome c oxidase subunit 4 |
Cpd | compound |
CPT1 | carnitine palmitoyltransferase 1 |
Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 |
Cyp2b2 | cytochrome P450, family 2, subfamily b, polypeptide 2 |
DEN | N-diethylnitrosamine |
DMF | N,N-dimethyl formamide |
DR5 | death receptor 5 |
DSS | dextran sulphate sodium |
ED2 | liver macrophages of the ED2 phenotype |
EFSA | European Food Safety Authority |
ERK | extracellular signal-regulated protein kinase |
EMIQ | enzymatically modified isoquercitrin |
FAS | fatty acid synthase |
FOS | Fos proto-oncogene |
GFAP | glial fibrillary acidic protein |
GLP-1 | glucagon-like peptide-1 |
GLUT4 | glucose transporter type 4 |
GMP | good manufacturing practices |
Gpx | glutathione peroxidase |
GRAS | generally recognized as safe |
Grin2d | glutamate ionotropic receptor NMDA type subunit 2D |
Gstm1 | glutathione S-transferase, mu 1 |
GST-P | glutathione S-tranferase placental form |
γ-GTP | gamma-glutamyl transpeptidase |
HO-1 | heme oxygenase-1 |
HOMA-IR | Homeostatic Model Assessment-Insulin Resistance; homeostatic model assessment for insulin resistance |
Iba1 | ionized calcium-binding adapter molecule 1 |
IFN-γ | type II interferon |
IgE | immunoglobulin E |
IL | interleukin |
IQ | isoquercitrin |
IQG | isoquercitrin with α-glucose moiety |
IQGn | isoquercitrin win n α-glucose moieties |
JAK | Janus kinase |
LD50 | median lethal dose |
LPH | lactase-phlorizin hydrolase |
LPS | lipopolysaccharide |
Kif21b | kinesin family member 21B |
MAPK | mitogen-activated protein kinase |
Mapk8 | mitogen-activated protein kinase 8 |
Mapk14 | mitogen-activated protein kinase 14 |
Mapkapk3 | mitogen-activated protein kinase-activated proteinkinase 3 |
MCAD | medium-chain acyl-CoA dehydrogenase |
MGAM | mucosal maltose-glucoamylase |
Me1 | malic enzyme 1 |
MN-RET | micronucleated reticulocyte(s) |
Mrp2 | multidrug resistance-associated protein 2; ATP-binding cassette, subfamily C, member 2 |
NADPH | reduced form of nicotinamide adenine dinucleotide phosphate |
NEFA | non-esterified fatty acid |
Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NOAEL | no-observed-adverse-effect level |
NOX | NADPH oxidase |
Ntrk2 | neurotrophic receptor tyrosine kinase 2 |
OECD | Organisation for Economic Cooperation and Development |
p.o. | per os; oral administration |
PCNA | proliferating cell nuclear antigen |
p-ERK1/2 | phospho-ERK1/2 |
PGC-1α | PPAR-γ coactivator 1α |
PPARα | peroxisome proliferator-activated receptor α |
PRDM 16 | PR-domain containing protein 16 |
QU | quercetin |
ROS | reactive oxygen species |
RT | rutin |
Serpine1 | serine (or cysteine) peptidase inhibitor, clade E, member 1 |
SGLT 1 | sodium-dependent glucose transporter 1 |
SHR | spontaneously hypertensive rat |
Slc17a6 | solute carrier family 17 member 6 |
SREBP1 | sterol regulatory element-binding protein 1 |
SSZ | sulfasalazine |
STAT | signal transducer and activator of transcription proteins |
TBARS | thiobarbituric acid reactive substances |
TGF-β | transforming growth factor β |
Tmax | time to reach Cmax |
TNF-α | tumor necrosis factor α |
Tnfrsf10b | tumor necrosis factor receptor superfamily, member 10b |
Tp53 | tumor protein p53 |
TUNEL | terminal deoxynucleotidyl transferase-mediated nick end labelining |
Txn1 | thioredoxin 1 |
UCP 1 | uncoupling protein 1 |
UDP | uridine 5′-diphosphate |
U.S. FDA | The United States Food and Drug Administration |
UV-C | ultraviolet C light |
VCO2 | carbon dioxide production |
VO2 | oxygen consumption |
WRS | water-restraint stress |
Yc2 | glutathione S-transferase Yc2 subunit |