Table 1.
Clinical characteristics of patients with crescentic IgA nephropathy according to the presence or absence of ANCAs.
| Patients | N = 17 | ANCA-Positive N = 5 (3 IgA/2 IgG) |
ANCA-Negative N = 12 |
* p-Value |
|---|---|---|---|---|
| Age (y) | 48 (27–75) | 54.6 (29–72) | 46 (27–75) | 0.51 |
| Sex | ||||
| Women | 9 (53%) | 3 (60%) | 6 (50%) | 0.5 |
| Men | 8 (47%) | 2 (40%) | 6 (50%) | 0.5 |
| Clinical presentation | ||||
| Hypertension | 12 (15%) | 4 (67%) | 8 (67%) | 0.52 |
| Edemas | 7 (41%) | 2 (40%) | 5 (36%) | 0.60 |
| Skin lesions | 4 (24%) | 2 (40%) | 2 (17%) | 0.33 |
| Lung involvement | 1 (6%) | 0 | 1 (8%) | 0.71 |
| Oligoanuria/Anuria | 2 (12%) | 1 (20%) | 1 (8%) | 0.51 |
| Nephrotic syndrome | 6 (35%) | 2 (40%) | 4 (33%) | 0.6 |
| Renal replacement therapy at diagnosis | 1 (5%) | 0 | 1 (8.3%) | 0.7 |
| Follow-up | ||||
| Renal replacement therapy dependence | 4 (23.5%) | 1 (20%) | 3 (25%) | 0.24 |
| Mortality | 4 (23.5%) | 1 (20%) | 3 (25%) | 0.3 |
* p-Value less than 0.05.