Figure 11.

An anesthetized rat, initially imaged after one hour of tidal ventilation, undergoes a ‘recruitment’ maneuver consisting of Positive End-Expiratory Pressure (PEEP), causing the average ADC to decrease. During a subsequent period of 100 min of tidal ventilation, mean ADC increases by approximately 20% due to localized atelectasis. Re-recruitment returns the ADC to baseline. The black arrows highlight regions of regionally reduced (left) or increased (right) ADC that appear immediately before or after recruitment. Reprinted from Cereda, et al. (J Appl Physiol 2011, ref. [43]) with permission.