PD |
Parkinson’s disease |
SN |
Substantia nigra |
STR |
Striatum |
TH |
Tyrosine hydroxylase |
UPS |
Ubiquitin–proteasome table system |
ERS |
Endoplasmic reticulum stress |
UBA52 |
Ubiquitin-60S ribosomal protein L40 |
UBB |
Polyubiquitin-B |
UBC |
Polyubiquitin-C |
RPS27a |
Ubiquitin-40S ribosomal protein S27a |
RT-qPCR |
Real-time quantitative PCR |
MS |
Mass spectrometry |
MALDI-TOF |
Matrix-assisted laser desorption ionization-time of flight |
ACN |
Acetonitrile |
ABC |
Ammonium Bicarbonate |
TFA |
Trifluro acetic acid |
IgG: |
Immunoglobulin G |
PQC |
Protein quality control |
PFFs |
Preformed fibrils |
PSOPIA |
Prediction server of protein–protein interaction |
HSP90 |
Heat shock protein 90 |
CHIP |
C-terminus of HSC-70 |
K48R |
Lysine residue mutated to arginine at position-48 of UBA52 |
K63R |
Lysine residue mutated to arginine at position-63 of UBA52 |
pJNK1 |
phospho- c-Jun N-terminal kinase 1 |
AKT1 |
RAC-alpha serine/threonine-protein kinase 1 |
PINK1 |
PTEN-induced kinase 1 |
HSP75 |
Heat shock protein 75 |