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. 2022 Nov 30;23(23):15046. doi: 10.3390/ijms232315046

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Comparison of SARS-CoV-2-specific B-cell subpopulations between recovered SARS-CoV-2 (+) (n = 5) and uninfected SARS-CoV-2 (−) (n = 6) vaccinated subjects at T4. (A) Percentage (%) of each SARS-CoV-2-specific B-cell subpopulations (naïve, IgD⁺CD27⁻; unswitched memory, IgD⁺CD27⁺; switched memory, IgD⁻CD27⁺; and late memory, IgD⁻CD27⁻) at T4 in both uninfected (white dots) and recovered subjects (red dots). (B) Percentage (%) of plasma blast (CD27^highCD38^high) in both uninfected SARS-CoV-2 (−) and recovered SARS-CoV-2 (+) subjects at T4. Significance was determined using the Mann–Whitney test and t-tests, * p < 0.0332.