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. 2022 Dec 6;15:6595–6605. doi: 10.2147/JIR.S383903

Table 3.

Patients Stratified by “TRS-2P”

Variable Low Risk Intermediate Risk High Risk P-value
(n= 100) (n = 90) (n = 107)
Age (year) 61 (14) 62 (16) 69 (17) <0.001
Male, n (%) 60 (60.00) 64 (71.11) 73 (68.22) 0.236
Smoking, n (%) 24 (24) 46 (51.11) 54 (50.47) <0.001
Hypertension, n (%) 53 (53) 55 (58.89) 88 (82.24) <0.001
T2DM, n (%) 17 (17) 26 (28.89) 47 (43.93) <0.001
NLRP3 (ng/mL) 3.09 (2.57) 3.76 (4.20) 4.63 (5.90) <0.001
WBC (×109/L) 6.33 (2.32) 8.77 (3.80) 8.89 (3.96) <0.001
CRP (mg/L) 1.14 (2.34) 3.20 (5.14) 3.16 (11.06) <0.001
D-dimer (ng/mL) 0.27 (0.36) 0.34 (0.48) 0.46 (0.7) <0.001
cTnI (ng/mL) 0.01 (0.05) 1.10 (4.71) 1.50 (7.85) <0.001
BNP (pg/mL) 82 (72) 389 (1161) 1320 (2577) <0.001
LDL (mmol/L) 2.56 (1.09) 2.92 (1.20) 2.59 (1.22) 0.092
Cr (mmol/L) 70.05 (21.70) 71.20 (20.05) 72.50 (26.60) 0.189
LVDD (mm) 45 (5) 47 (7) 45 (6) 0.025
LVEF (%) 62 (4) 54 (16) 48 (17) <0.001

Abbreviations: T2DM, type 2 diabetes mellitus; NLRP3, NACHT, LRR, and PYD domain-containing protein 3; WBC, white blood cell; CRP, C-reactive protein; cTnI, Troponin I; BNP, type B natriuretic peptide; LDL, low-density lipoprotein cholesterol; Cr, creatinine; LVDD, left ventricular end-diastolic dimension; LVEF, left ventricle ejection fraction.