Histological sections of ticks in the SC tissue of red foxes from Italy. (A): moderate mixed infiltrate composed by neutrophils, lymphocytes and rare eosinophils surrounding the tick (a). Fragments of tick exoskeleton surrounded by inflammatory cells (b) and a complete multilayer connective tissue capsule surrounding the tick body (c) (Masson’s trichrome, bar 500 µm). (B): The inner part of the tick was composed of cell debris and a multilayer connective tissue capsule surrounding the tick body (HE, bar 300 µm). (C): mild mixed infiltrate surrounding the tick, and a thin connective tissue capsule (HE, 150 µm).