Skip to main content
. 2022 Nov 27;23(23):14840. doi: 10.3390/ijms232314840

Table 2.

SBs mononuclear metal complexes with antimalarial, antioxidant, antidiabetic, and anti-Alzheimer activities.

Structure Compound % Inhibition, MIC, and IC50 K i Ref
graphic file with name ijms-23-14840-i020.jpg Zn(BZ-PCBPMP)2 (20) MIC = 0.56 μmol/L
(P. falciparum)
- Shaikh et al., 2022 [74]
graphic file with name ijms-23-14840-i021.jpg Fe(III) complex (21) % inhib: 65.54%
(antimalarial)
% inhib: 52–54%
(α-amylase)
% inhib: 94.27%
(DPPH)
- Ragole et al., 2022 [75]
graphic file with name ijms-23-14840-i022.jpg 22 IC50 = 12.45 µM
(AChE)
IC50 = 9.61 µM
(BChE)
IC50 = 35.57 µM
(α-glycosidase)
Ki = 11.92 ± 3.90 µM (AChE)
Ki = 6.98 ± 0.96 µM
(BChE)
Ki = 38.17 ± 6.26 µM
(α-glycosidase)
Şenocak et al., 2021 [76]
graphic file with name ijms-23-14840-i023.jpg 23 IC50 = 7.24 µM
(AChE)
IC50 = 4.73 µM
(BChE)
IC50 = 30.84 µM
(α-glycosidase)
Ki = 6.26 ± 0.83 µM (AChE)
Ki = 3.68 ± 0.54 µM (BChE)
Ki = 37.14 ± 7.12 µM (α-glycosidase)
Şenocak et al., 2021 [76]
graphic file with name ijms-23-14840-i024.jpg 24 IC50 = 18.06 µM (AChE)
IC50 = 11.25 µM
(BChE)
IC50 = 26.21 µM
(α-glycosidase)
Ki = 15.73 ± 4.73 µM (AChE)
Ki = 10.27 ± 1.68 µM (BChE)
Ki = 30.50 ± 3.82 µM (α-glycosidase)
Şenocak et al., 2021 [76]
graphic file with name ijms-23-14840-i025.jpg 25 IC50 = 1.41 ± 0.03 μmol/mL
(α-amylase)
IC50 = 0.62 ± 0.07 μmol/mL
(α-glucosidase)
- Deswal et al., 2022 [78]
graphic file with name ijms-23-14840-i026.jpg 26 IC50 = 1.33 ± 0.05 μmol/mL
(α-amylase)
IC50 = 0.60 ± 0.05 μmol/mL
(α-glucosidase)
- Deswal et al., 2022 [78]