Table 2.
Structure | Compound | % Inhibition, MIC, and IC50 | K i | Ref |
---|---|---|---|---|
Zn(BZ-PCBPMP)2 (20) | MIC = 0.56 μmol/L (P. falciparum) |
- | Shaikh et al., 2022 [74] | |
Fe(III) complex (21) | % inhib: 65.54% (antimalarial) % inhib: 52–54% (α-amylase) % inhib: 94.27% (DPPH) |
- | Ragole et al., 2022 [75] | |
22 | IC50 = 12.45 µM (AChE) IC50 = 9.61 µM (BChE) IC50 = 35.57 µM (α-glycosidase) |
Ki = 11.92 ± 3.90 µM (AChE) Ki = 6.98 ± 0.96 µM (BChE) Ki = 38.17 ± 6.26 µM (α-glycosidase) |
Şenocak et al., 2021 [76] | |
23 | IC50 = 7.24 µM (AChE) IC50 = 4.73 µM (BChE) IC50 = 30.84 µM (α-glycosidase) |
Ki = 6.26 ± 0.83 µM (AChE) Ki = 3.68 ± 0.54 µM (BChE) Ki = 37.14 ± 7.12 µM (α-glycosidase) |
Şenocak et al., 2021 [76] | |
24 | IC50 = 18.06 µM (AChE) IC50 = 11.25 µM (BChE) IC50 = 26.21 µM (α-glycosidase) |
Ki = 15.73 ± 4.73 µM (AChE) Ki = 10.27 ± 1.68 µM (BChE) Ki = 30.50 ± 3.82 µM (α-glycosidase) |
Şenocak et al., 2021 [76] | |
25 | IC50 = 1.41 ± 0.03 μmol/mL (α-amylase) IC50 = 0.62 ± 0.07 μmol/mL (α-glucosidase) |
- | Deswal et al., 2022 [78] | |
26 | IC50 = 1.33 ± 0.05 μmol/mL (α-amylase) IC50 = 0.60 ± 0.05 μmol/mL (α-glucosidase) |
- | Deswal et al., 2022 [78] |