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The age-related changes in mtDNA in the cerebral cortex in the three age groups of mice. (A) The mean number of damages through all studied fragments of mtDNA. (B) Normalized mtDNA level in the frontal cortex * p < 0.05, ** p < 0.01 differences between age groups were statistically significant according to the Mann–Whitney test. The 2-month-old mice (n = 9), 7-month-old mice (n = 9), 15-month-old mice (n = 9).
