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. 2022 Dec 2;23(23):15197. doi: 10.3390/ijms232315197

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The results of the open field test for the three age groups. (A) Locomotor activity (s); (B) rearing acts (quantity); (C) entering to the center (quantity); (D) time in the center area (s); (E) grooming acts (quantity); (F) grooming time (s); (G) hole-poking acts (quantity); (H) defecation acts (quantity). * p < 0.05; ** p < 0.01 differences between age groups were statistically significant according to the Mann–Whitney test. The 2-month-old mice (n = 9), 7-month-old mice (n = 9), 15-month-old mice (n = 9).