Table 1.
Number of mtDNA lesions in the cerebral cortex in the three age groups of mice.
| Fragment | Number of mtDNA Lesions (per 10 kb) | ||
|---|---|---|---|
| 2-Month-Old | 7-Month-Old | 15-Month-Old | |
| 12–16s (1st) | 2.36 ± 0.39 | 4.01 ± 0.37 ** | 3.34 ± 0.30 |
| 16s-Nd1 (2nd) | 2.45 ± 0.41 | 3.59 ± 0.71 | 4.11 ± 0.29 * |
| Nd1-Nd2 (3th) | 1.03 ± 0.36 | 2.86 ± 0.62 * | 2.05 ± 0.15 |
| Nd5 (4th) | 1.97 ± 0.43 | 3.12 ± 0.51 | 2.65 ± 0.11 |
| Nd6-CytB (5th) | 2.16 ± 0.34 | 1.89 ± 0.59 | 2.73 ± 0.19 |
| D-loop (6th) | 3.89 ± 0.54 | 3.02 ± 0.67 | 5.44 ± 0.07 ***†† |
* p < 0.05; ** p < 0.01; *** p < 0.001 differences are statistically significant compared with the 2-month-old mice group. †† p < 0.01 differences are statistically significant for the 15-month-old compared with the 7-month-old mice group. The 2-month-old mice (n = 9), 7-month-old mice (n = 9), 15-month-old mice (n = 9).