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. 2022 Nov 22;27(23):8127. doi: 10.3390/molecules27238127

Figure 2.

Figure 2

Mebendazole inhibits the viability, proliferation and migration of PDAC cell lines: (a–c) cytotoxic effect exerted by MBZ, RB005, PF543, FTY720 and gemcitabine treated with 20 and 40 µM each on PDAC cell lines: MIA PaCa-2, Panc-1 and Capan-1, respectively; (d) colony formation in MIA PaCa-2 cell line after 24 h treatment with different concentrations (1.25 µM, 2.5 µM, 5 µM, 10 µM and 20 µM) of MBZ; (e) transwell migration of MIA PaCa-2 cell after 24 h treatment with 20 µM concentration of MBZ, RB005, PF543, FTY720 and gemcitabine. All experiments were carried out three times and data were illustrated on mean ± S.D, * p < 0.05, ** p < 0.01 and *** p < 0.001.