Figure 3.
Correlation of expression of 14 DEGs with methylation levels of 17 neighboring DMPs. Cyan and pink dots represent HCM and AS patients, respectively. The black regression line and its confidential interval (gray area) are shown on each plot. Spearman’s rank correlation coefficients and p-values calculated for each of the 17 DEG–DMP pairs are presented above corresponding dot plots. Significant coefficients and p-values are marked in bold. Location of DMPs according to gene functional elements and CpG landmarks are indicated under each plot. TSS1500 and TSS200—regions within 1500-200 and 200-0 nucleotides upstream from the transcription start site (TSS), respectively; 5’UTR and 3’UTR—5′ and 3′ untranslated regions, respectively. NS—not significant.