Table 3.
Analysis of association of SNPs with levels of loneliness (SOLTOT) based of lineal regression. The models with significant p and the lowest Akaike’s Information Criterion (AIC) and Bayesian Information Criterion (BIC) are presented.
| SNP | Model | Genotype | n | Response Mean (s.e.) | Difference (95% CI) | p-Value |
|---|---|---|---|---|---|---|
| rs12335203 | Log-additive | CC | 95 | 2.41 (0.18) | −0.31 (−0.57–−0.05) | 0.018 |
| CT | 161 | 1.99 (0.13) | ||||
| TT | 64 | 1.81 (0.2) | ||||
| rs391300 | Dominant | CC | 105 | 2.49 (0.17) | 0 | |
| CT/TT | 214 | 1.87 (0.11) | −0.61 (−0.99–−0.23) | 0.0018 | ||
| rs2487999 | Log-additive | CC | 259 | 1.98 (0.1) | 0.47 (0.05–0.88) | 0.029 |
| CT | 57 | 2.44 (0.25) | ||||
| TT | 4 | 3 (0.41) | ||||
| rs2154110 | Overdominant | TT/GG | 199 | 2.29 (0.12) | 0 | |
| GT | 121 | 1.73 (0.14) | −0.56 (−0.93–−0.19) | 0.0035 | ||
| rs4902100 | Codominant | AA | 183 | 2.21 (0.13) | 0 | |
| AG | 117 | 1.74 (0.15) | −0.45 (−0.83–−0.07) | 0.0061 | ||
| GG | 20 | 2.85 (0.25) | ||||
| rs6265 | Codominant | CC | 197 | 1.88 (0.11) | 0 | |
| CT | 113 | 2.27 (0.17) | 0.39 (0.01–0.76) | 0.0002 | ||
| TT | 10 | 3.9 (0.5) | 2.02 (1.00–3.05) |