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. 2022 Dec 1;23(23):15109. doi: 10.3390/ijms232315109

Figure 2.

Figure 2

Multiple roles of natural-product-mediated autophagy regulation in HCC. (A) Natural products protect against HCC by inhibiting autophagy. ADCX, 25-O-acetyl-7,8-didehydrocimigenol 3-O-beta-D-xylopyranoside; PB, aqueous extract of polygonum bistorta; IS, icariside II. (B) Natural products exert anti-HCC effects by inducing autophagy. rBTI, Recombinant buckwheat trypsin inhibitor; QCT, quercetin; XAG, xanthoangelol; DHA, dihydroartemisinin; SK, Shikonin. (C) Autophagy activation is considered as a side effect associated with anti-HCC activities of natural products. GA, 18β-Glycyrrhetinic-acid.