Table 2.
Studies investigating ctHPV DNA as a cancer surveillance tool after definitive treatment.
| Author/Trial Name | Number of Cases | Study Design |
Detection Method | Definitive Treatment |
|---|---|---|---|---|
| Cao et al. [33] | 14 | SI, RA | qPCR | CRT |
| Routman et al. [43] | 32 | SI, RA | qPCR | Surgery |
| Ahn et al. [8] | 93 | SI, RA | qPCR | CRT/surgery |
| Berger et al. [44] | 1076 | MI, RA | ddPCR | CRT/surgery |
| Agrawal et al. [45] | 135 | SI, RA | qPCR | CRT/surgery |
| Veyer et al. [29] | 66 | SI, RA | ddPCR | CRT/surgery |
| Haring [46] | 34 | SI, PA | ddPCR | CRT/Surgery |
| Chera [47] | 115 | SI, PA | qPCR | CRT |
| Rutkowski [48] | 66 | SI, RA | qPCR | CRT |
SI—single institutional study; MI—multi-institutional study; RA—retrospective analysis; PA—prospective analysis.