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. 2022 Nov 26;14(23):5826. doi: 10.3390/cancers14235826

Figure 4.

Figure 4

Nano-CT scans and pathological analyses. Nano-CT scans of intracranial tumor (A) and extracranial tumor (B). Exemplified cases receiving VDA of intracranial tumor (C), and extracranial tumor (D) after staining by H&E, CD31, and Ki67. Comparison of relative vascular density of brain tumor tissue compared with contralateral brain tissue (E), necrosis area (F), Ki67-positive rate (G), CD31-positive rate (H), and vascular area delineated by CD31 staining by pathology of either intracranial or extracranial tumor (I). Abbreviations: VDA: vascular-disrupting agent, CD31: cluster of differentiation 31 for vascular endothelia, Ki67: a nuclear protein marker for proliferating cells, *: p < 0.05, **: p < 0.01, ***: p < 0.001, ****: p < 0.0001.