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. 2022 Nov 28;12(23):3322. doi: 10.3390/ani12233322

Table 2.

A list of studies since 2000 describing effects of 3- and 6-phytase supplemented individually at different levels in diets for nursery pigs.

Duration, Day of Age Type Activity,
FTU/kg Feed
% Change * Reference **
42–70 3-phytase 0–1200 ADG 1 (14%), G:F 2 (8%), inorganic plasma P 3 (6%) [160]
28–63 3-phytase 0–2500 ADG (21%), Ca 4 digestibility (20%), P digestibility (60%) [161]
15–38 3-phytase 0–400 ADG (20%), G:F (12%), bone ash (15%) [90]
21–56 3-phytase 0–1250 ADG (34%), ADFI 5 (19%), G:F (18%) [162]
18–46 3-phytase 0–500 Stomach phytate hydrolysis (75%), ileum phytate hydrolysis (15%), rectum phytate hydrolysis (15%), bone ash (19%), P digestibility (40%), histidine digestibility (7%) [163]
18–32 3-phytase 0–500 ADG (15%), plasma P (89%), liver P (6%) [164]
27–46 3-phytase 0–750 ADFI (8%), plasma zinc, (54%), plasma alkaline phosphatase activity (67%), bone zinc (43%), liver zinc (26%) [165]
27–46 3-phytase 0–700 ADG (22%), ADFI (14%), G:F (22%), plasma zinc (71%), plasma P (10%), alkaline phosphatase activity (71%), bone ash (9%), bone zinc (48%), bone P (2%) [166]
31–59 3-phytase 0–1000 ADG (17%), bone ash (6%), Ca digestibility (23%), P digestibility (68%) [103]
18–46 3-phytase 0–350 ADG (6%), ADFI (6%), G:F (4%), bone ash (4%), bending moment (16%) [167]
28–70 3-phytase 0–750 ADG (6%), final body weight (5%) [168]
ND 6 6-phytase 0–500 Ca digestibility (13%), P digestibility (40%) [169]
ND 6-phytase 0–600 ADG (11%), body weight (7%), plasma P (24%) [170]
18–37 6-phytase 0–500 G:F (1%), no changes in other parameters [171]
20–34 6-phytase 0–500 Plasma zinc (5%), Ca retention (4%), P retention (3%) [172]
28–71 6-phytase 0–15,000 ADG (28%), ADFI (22%), G:F (9%), ash digestibility (25%), Ca digestibility (25%), P digestibility (60%) [173]
30–58 6-phytase 0–12,500 ADG (34%), ADFI (17%), G:F (22%), BBS 7 (51%), ash content (47%), P absorption (63%), Ca absorption (46%), N 8 absorption (36%) [174]
42–84 6-phytase 0–2000 Femur strength yield-bending moment (12%), femur strength strain (17%), femur strength maximum bending moment (3%), femur zinc content (17%) [175]
26–47 6-phytase 0–500 ADG (17%), G:F (11%), CP 9 digestibility (9%), P digestibility (16%), bone ash (6%), bone P (4%) [176]
21–63 6-phytase 0–2500 ADG (2%), final body weight (1%), serum P (5%), serum zinc (60%) [177]
28–56 6-phytase 0–20,000 ADG (22%), ADFI (14%), G:F (9%), BBS (43%), bone ash weight (28%), DM 10 digestibility (4%), GE digestibility (4%), CP digestibility (5%), Ca digestibility (36%), P digestibility (49%), inositol hexaphosphate digestibility (86%), lysine digestibility (5%), threonine digestibility (6%), valine digestibility (5%) [178]
35–63 6-phytase 0–20,000 ADG (22%), FCR 11 (−11%), DM digestibility (2%), GE 12 digestibility (2%), CP digestibility (4%), Ca digestibility (37%), P digestibility (52%), BBS (37%), bone ash (32%), bone Ca (35%), plasma P (14%) [179]
28–48 6-phytase 0–2500 ADG (20%), P fecal digestibility (23%), plasma copper (−21%) [180]
40–61 6-phytase 0–1000 ADG (15%), ADFI (56%), G:F (10%), bone weight (24%), bone ash (15%) [181]
21–63 6-phytase 0–4000 ADG (7%), G:F (3%), bone ash (10%) [182]
28–70 6-phytase 0–2500 ADFI (−9%), FCR (−8%), stomach pH (−20%) [183]
21–62 6-phytase 0–4000 ADG (21%), ADFI (25%), P digestibility (54%), BBS (28%), bone ash (14%) [184]
32–41 6-phytase 0–2000 AID 13 (27%) and ATTD 14 (46%) of P, ATTD of Ca (16%), N digestibility (11%), inositol hexaphosphate digestibility (53%), lysine digestibility (8%), threonine digestibility (8%), valine digestibility (9%) [185]
21–70 6-phytase 0–2000 ADG (35%), ADFI (17%), G:F (11%), P digestibility (26%), Ca digestibility (14%), Ca absorption (37%), P absorption (32%), plasma myo-inositol (39%), duodenum myo-inositol (68%), ileum myo-inositol (87%), inositol hexaphosphate hydrolysis (98%) [186]
ND 6-phytase 0–2000 ADG (7%), ADFI (6%), G:F (1%) [187]
21–42 6-phytase 0–1000 ADG (27%), ADFI (13%), BBS (48%), bone ash (22%), bone Ca (17%), bone P (25%) [188]
31–59 6-phytase 0–3000 ADG (13%), AID (48%) and ATTD (31%) of P, GLUT2 15 gene expression (55%), ASCT2 16 gene expression (37%), CLDN3 17 gene expression (41%), duodenum-jejunum Inositol hexaphosphate (−92%), ileum inositol hexaphosphate (−95%), duodenum-jejunum myo-inositol (67%), ileum myo-inositol (80%) [189]
ND 6-phytase 0–500 ADG (18%), G:F (9%), bone ash (4%) [190]
35–77 6-phytase 0–4000 ADG (45%), bone mineral density (15%), bone mineral content (17%), fecal Lachnospiraceae (ND), fecal Succinvibrio (ND), fecal Bifidobacterium (ND) [191]
ND 6-phytase 0–16,000 Stomach pH (−16%), fecal score (−14%), diarrhea frequency (−41%) [192]
26–68 6-phytase 0–500 ADG (22%), ADFI (15%), Ca digestibility (25%), P digestibility (78%), bone ash (18%) [193]
21–66 6-phytase 0–5000 ADG (20%), BBS (33%), bone ash (9%), P bone content (12%), CP digestibility (3%), EE 18 digestibility (11%), P digestibility (6%) [84]

* The described effects were in comparison with treatments without phytase supplementation. Described effects were considered significant with p < 0.05 and tendency with 0.05 ≤ p < 0.10. ** The references were selected from peer-reviewed literature available after 2000. 1 Average daily gain. 2 Gain to feed ratio. 3 Phosphorus. 4 Calcium. 5 Average daily feed intake. 6 No data. 7 Bone breaking strength. 8 Nitrogen 9 Crude protein. 10 Dry matter. 11 Feed conversion ratio. 12 Gross energy. 13 Apparent ileal digestibility. 14 Apparent total tract digestibility. 15 Glucose transporter type 2. 16 Neutral amino acid transporter. 17 Claudin 3. 18 Ether extract.