Table 3.
Incidence of MN, cytokinesis-block proliferation index, distribution of MN per cell and frequency of MN, measurement in cell cultures of human lymphocytes treated with different concentrations of A. vulgaris extract.
| Conc. µg/mL |
% Bn Cell with MN |
MN/Bn Cell |
CBPI | Frequency of MN |
|---|---|---|---|---|
| Control | 2.1 ± 0.11 | 1.2 ± 0.06 | 1.6 ± 0.02 | 100% |
| Amifos.—1.0 µg/mL | 1.8 ± 0.14 | 1.2 ± 0.09 | 1.7 ± 0.02 | (81.4%) − 18.6% |
| MMC—0.2 µg/mL | 2.8 ± 0.10 | 1.2 ± 0.02 | 1.6 ± 0.03 | (124.2%) + 24.2% |
| A. vulgaris—2 µg/mL | 1.7 ± 0.09 | 1.2 ± 0.06 | 1.7 ± 0.01 | (79.5%) − 20.5% |
| A. vulgaris—4 µg/mL | 1.6 ± 0.03 | 1.3 ± 0.05 | 1.7 ± 0.06 | (81.8%) − 18.2% |
| A. vulgaris—6 µg/mL | 1.8 ± 0.06 | 1.2 ± 0.04 | 1.6 ± 0.02 | (83.7%) − 16.3% |
% Bn cells with micronuclei. MN/Bn cells—incidence of micronuclei in binucleated cells. CBPI—cytokinesis-block proliferation index. Frequency of MN—incidence of MN present as % from control groups in cell cultures of human lymphocytes treated with different concentrations of A. vulgaris extract.