TABLE 2.

Bacterial clearance during established infection^a

Expt	Treatment	Tissue	Admin. day	Analysis day p.i.	Infectivity index
2	None	Liver		10	4
1	None	Liver		10	5
1	None	Spleen		10	5
2	None	Liver		11	4
2	None	Liver		13	4
1	None	Liver		17	5
2	None	Liver		17	5
1	None	Spleen		17	5
2	None	Liver		18	5
2	None	Liver		20	5
3	None	Liver		21	4
3	None	Liver		21	4
3	None	Liver		21	5
1	None	Liver		24	5
1	None	Spleen		24	5
1	ISb	Liver	3	10	0
1	IS	Spleen	3	10	0
1	IS	Liver	3	17	1
1	IS	Spleen	3	17	1
2	IS	Liver	10	11	5
2	IS	Liver	10	13	3
1	IS	Liver	10	17	2
2	IS	Liver	10	17	2
1	IS	Spleen	10	17	2
2	IS	Liver	10	20	1
1	IS	Liver	10	24	2
1	IS	Spleen	10	24	2
2	IS	Liver	17	18	5
2	IS	Liver	17	20	2
3	IS	Liver	17	21	0
3	IS	Liver	17	21	2
1	IS	Liver	17	24	3
1	IS	Spleen	17	24	3
1	IS	Liver	17	31	3
1	IS	Spleen	17	31	3

^aSemiquantitative PCR data from three experiments were normalized and sorted as shown. The QPCR data from experiments 1 and 2 are shown in Fig. 4a and 4b and c, respectively. Both liver and spleen tissues were analyzed in experiment 1. Comparison of the combined data from the control and serum-treated groups revealed high statistical significance (P = 0.0001). Admin., administration; p.i. postinfection. 

^bIS, immune serum.