Table 1.
Pathway enrichment analysis of GO terms in ShinyGo, sorted by average ranks (FDR and fold).
| GO TERMS | Gene Number (Pathway Gene Number) |
Fold Enrichment |
Enrichment FDR |
|---|---|---|---|
| Biological Process | |||
| Presynapse assembly | 11 (52) | 8.3 | 1.02 × 10−5 |
| Coronary vasculature morphogenesis | 6 (16) | 14.8 | 1.79 × 10−4 |
| Presynapse organisation | 11 (55) | 7.9 | 1.83 × 10−5 |
| Coronary vasculature development | 9 (46) | 7.7 | 1.95 × 10−4 |
| Synaptic membrane adhesion | 7 (28) | 9.8 | 3.69 × 10−4 |
| Positive regulation of TGF-β signalling pathway | 7 (30) | 9.2 | 5.32 × 10−4 |
| Positive regulation of cellular response to TGF-β stimulus | 7 (30) | 9.2 | 5.32 × 10−4 |
| Ventricular septum development | 11(72) | 6.0 | 1.92 × 10−4 |
| Cardiac septum development | 14 (108) | 5.1 | 7.89 × 10−5 |
| Ventricular compact myocardium morhogenesis | 4 (8) | 19.7 | 1.23 × 10−3 |
| Molecular Function | |||
| SMAD binding | 14 (80) | 6.9 | 2.44 × 10−6 |
| RNA strand annealing activity | 3 (5) | 23.7 | 5.l0 × 10−3 |
| Insulin-like growth factor I binding | 4 (13) | 12.1 | 7.17 × 10−3 |
| β-catenin binding | 13 (89) | 5.7 | 2.58 × 10−5 |
| RNA stem-loop binding | 4 (14) | 11.3 | 9.53 × 10−3 |
| Poly-purine tract binding | 6 (29) | 8.1 | 2.71 × 10−3 |
| Transcription factor binding | 42 (596) | 2.7 | 2.36 × 10−6 |
| Poly(G) binding | 3 (8) | 14.8 | 1.80 × 10−2 |
| DNA-binding transcription repressor activity. RNA polymerase II-specific | 21 (333) | 2.4 | 4.50 × 10−3 |
| 3,5-cyclic-AMP phosphodiesterase activity | 4 (16) | 9.8 | 1.52 × 10−2 |
| Cellular Component | |||
| Cytoplasmic ribonucleoprotein granule | 23 (272) | 3.3 | 5.56 × 10−5 |
| GABA-ergic synapse | 9 (74) | 4.8 | 4.56 × 10−3 |
| Ribonucleoprotein granule | 23 (288) | 3.1 | 1.29 × 10−4 |
| Node of Ranvier | 4 (15) | 10.5 | 1.l0 × 10−2 |
| Filopodium | 11 (119) | 3.6 | 7.40 × 10−3 |
| Glutamatergic synapse | 25 (358) | 2.7 | 4.44 × 10−4 |
| Site of polarised growth | 15 (196) | 3.0 | 6.17 × 10−3 |
| Chromatin | 76 (1316) | 2.2 | 8.70 × 10−9 |
| Adherens junction | 14 (180) | 3.0 | 7.33 × 10−3 |
| Heterochromatin | 8 (77) | 4.1 | 1.62 × 10−2 |