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. 2022 Nov 23;14(23):5756. doi: 10.3390/cancers14235756

Table A5.

Comparison of frequency of clinical features in the 2 years prior to diagnosis between NSCLC and SCLC.

All Patients
(n = 711)
NSCLC and SCLC (n = 609) NSLCL (n = 546) SCLC (n = 63) p-Value
Cough 573 (80.59%) 505 (82.9%) 450 (82.4%) 55 (87.3%) 0.4245
Shortness of breath 515 (72.43%) 445 (73.1%) 398 (72.9%) 47 (74.6%) 0.8889
Fatigue 476 (66.95%) 412 (67.7%) 368 (67.4%) 44 (69.8%) 0.8025
Chest Pain 403 (56.68%) 356 (58.5%) 316 (57.9%) 40 (63.5%) 0.4706
Chest crackles or wheeze 397 (55.84%) 342 (56.2%) 302 (55.3%) 40 (63.5%) 0.2692
Back pain 350 (49.23%) 301 (49.4%) 271 (49.6%) 30 (47.6%) 0.8652
Weight loss 308 (43.32%) 260 (42.7%) 237 (43.4%) 23 (36.5%) 0.3609
Bone pain 270 (37.97%) 244 (40.1%) 222 (40.7%) 22 (34.9%) 0.4567
Lymphadenopathy 151 (21.24%) 131 (21.5%) 110 (20.1%) 21 (33.3%) 0.0244
Hemoptysis 118 (16.60%) 98 (16.1%) 88 (16.1%) 10 (15.9%) 1.0000
Finger clubbing 39 (5.49%) 33 (5.4%) 32 (5.9%) 1 (1.6%) 0.2607

Footnotes: Excludes individuals with stage 0 or unknown stage. Excludes asymptomatic people but includes screen-detected individuals.