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. 2022 Nov 24;11(23):6923. doi: 10.3390/jcm11236923

Table 3.

Diagnostic performance of six plasma cytokines for lung cancer in a development cohort.

Cytokines p-Value AUC (95% CI) Sensitivity (%) (95% CI) Specificity (%) (95% CI)
IL-6 <0.0001 0.6726 (0.6102 to 0.7349) 67.55 (59.46% to 74.93%) 60.13 (51.91% to 67.95%)
IL-8 0.0002 0.7174 (0.6166 to 0.8182) 66.00 (51.23% to 78.79%) 68.00 (53.30% to 80.48%)
IL-10 0.0001 0.7179 (0.6156 to 0.8202) 67.31 (52.89% to 79.67%) 76.00 (61.83% to 86.94%)
IL-12p70 <0.0001 0.7650 (0.6688 to 0.8612) 72.00 (57.51% to 83.77%) 74.00 (59.66% to 85.37%)
IFN-γ <0.0001 0.7394 (0.6418 to 0.8370) 73.08 (58.98% to 84.43%) 68.00 (53.30% to 80.48%)
TNF-α <0.0001 0.7499 (0.6488 to 0.8510) 69.81 (55.66% to 81.66%) 73.33 (58.06% to 85.40%)

AUC, the area under receiver operating characteristic curve; CI, confidence interval.