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Bioluminescence imaging can be used to measure longitudinal responses. (A,B), Example of bioluminescence signal at E10, E12 and E14 monitoring ex ovo growth of an untreated MESO-8T tumour nodule. (C) Proposed experimental timeline for BLI imaging to evaluate xenografts pre- and post-dosing. (D,E) Comparison of bioluminescence signal for in ovo MSTO-211H tumour nodules at E10 and E14, following two yolk sac injections of PBS at E10 and E12 (n = 8).
