Table 3.
Results of multivariable-adjusted models for the relation between serum and dietary magnesium and imaging markers of subclinical cardiovascular disease.
| Serum Magnesium | Dietary Magnesium | |||||
|---|---|---|---|---|---|---|
| Estimate | 95% CI | p Value | Estimate | 95% CI | p Value | |
| Left Ventricular Function | N = 366 | N = 287 | ||||
| Early diastolic filling rate (mL/s) | −3.29 | (−14.24, 7.67) | 0.556 | 0.17 | (−0.217, 0.556) | 0.388 |
| Late diastolic filling rate (mL/s) | −0.18 | (−11.17, 10.81) | 0.975 | 0.05 | (−0.347, 0.453) | 0.794 |
| End diastolic volume (mL/m2) | −0.86 | (−2.32, 0.58) | 0.239 | 0.06 | (0.014, 0.114) | 0.013 |
| End systolic volume (mL/m2) | −0.07 | (−0.94, 0.79) | 0.871 | 0.04 | (0.008, 0.065) | 0.011 |
| Stroke volume (mL/m2) | −0.81 | (−1.72, 0.10) | 0.082 | 0.03 | (−0.006, 0.059) | 0.104 |
| Cardiac output (mL/min/m2) | −52.73 | (−111.58, 6.11) | 0.078 | 1.42 | (−0.631, 3.471) | 0.174 |
| Ejection fraction (%) | −0.38 | (−1.16, 0.41) | 0.341 | −0.02 | (−0.048, 0.004) | 0.101 |
| Peak ejection rate (mL/s) | 5.38 | (−7.66, 18.42) | 0.418 | −0.22 | (−0.685, 0.253) | 0.365 |
| Myocardial mass (g/m2) | 0.003 | (−1.17, 1.18) | 0.995 | −0.01 | (−0.052, 0.028) | 0.546 |
| LGE | OR 3.06 | (1.27, 8.32) | 0.018 | OR 1.01 | (0.988, 1.036) | 0.434 |
| Remodeling index (g/mL/m2) | 0.005 | (−0.009, 0.019) | 0.479 | −0.001 | (−0.001. −0.0002) | 0.004 |
| Mean diastolic thickness (mm/m2) | 0.02 | (−0.04, 0.08) | 0.565 | −0.002 | (−0.004, −0.0002) | 0.029 |
| Right ventricular function | (N = 336) | (N = 236) | ||||
| End diastolic volume (mL/m2) | −1.74 | (−3.50, 0.02) | 0.053 | 0.05 | (−0.011, 0.114) | 0.105 |
| End systolic volume (mL/m2) | −1.21 | (−2.39, −0.04) | 0.043 | 0.03 | (−0.011, 0.071) | 0.171 |
| Stroke volume (mL/m2) | −0.53 | (−1.47, 0.41) | 0.268 | 0.02 | (−0.011, 0.056) | 0.187 |
| Cardiac output (mL/min/m2) | −32.62 | (−93.93, 28.70) | 0.296 | 1.51 | (−0.852, 3.474) | 0.169 |
| Ejection fraction (%) | 0.33 | (−0.38, 1.04) | 0.362 | −0.01 | (−0.034, 0.014) | 0.441 |
| Carotid plaque | (N = 248) | (N = 188) | ||||
| Presence of plaque | OR 1.62 | (1.07, 2.56) | 0.033 | OR 0.99 | (0.975,1.000) | 0.056 |
| Presence of plaque type | OR 1.58 | (1.19, 2.11) | 0.002 | OR 0.99 | (0.980, 0.996) | 0.004 |
| Wall thickness left (mm) | −0.003 | (−0.016, 0.009) | 0.66 | −0.0001 | (−0.0006, 0.0003) | 0.562 |
| Wall thickness right (mm) | −0.008 | (−0.019, 0.004) | 0.211 | −0.0001 | (−0.0006, 0.0002) | 0.381 |
All models are adjusted for age, sex, BMI, systolic blood pressure, and diabetes. Daily caloric intake was additionally adjusted for models with dietary magnesium. Serum cholesterol and smoking status were additionally adjusted for the association between serum magnesium and LGE, presence and type of plaque. Estimates represent β-estimates from linear regression or OR from logistic regression.